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Title:

Lack of replication in polymorphisms reported to be associated with atrial fibrillation.

Document type:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Author(s):
Sinner, MF; Lubitz, SA; Pfeufer, A; Makino, S; Beckmann, BM; Lunetta, KL; Steinbeck, G; Perz, S; Rahman, R; Sonni, A; Greenberg, SM; Furie, KL; Wichmann, HE; Meitinger, T; Peters, A; Benjamin, EJ; Rosand, J; Ellinor, PT; Kääb, S
Abstract:
Atrial fibrillation (AF) is the most common sustained arrhythmia and has a substantial heritable component. Numerous associations between single nucleotide polymorphisms (SNPs) and AF have been described, but few have been replicated.We sought to systematically replicate SNPs that are reported to be associated with AF in two large study samples of European descent.We searched PubMed for studies reporting associations between SNPs and AF published before July 1, 2007. SNPs were genotyped in two i...     »
Journal title abbreviation:
Heart Rhythm
Year:
2011
Journal volume:
8
Journal issue:
3
Pages contribution:
403-9
Language:
eng
Fulltext / DOI:
doi:10.1016/j.hrthm.2010.11.003
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21056700
Print-ISSN:
1547-5271
TUM Institution:
Institut für Humangenetik
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