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Titel:

Lack of replication in polymorphisms reported to be associated with atrial fibrillation.

Dokumenttyp:
Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Autor(en):
Sinner, MF; Lubitz, SA; Pfeufer, A; Makino, S; Beckmann, BM; Lunetta, KL; Steinbeck, G; Perz, S; Rahman, R; Sonni, A; Greenberg, SM; Furie, KL; Wichmann, HE; Meitinger, T; Peters, A; Benjamin, EJ; Rosand, J; Ellinor, PT; Kääb, S
Abstract:
Atrial fibrillation (AF) is the most common sustained arrhythmia and has a substantial heritable component. Numerous associations between single nucleotide polymorphisms (SNPs) and AF have been described, but few have been replicated.We sought to systematically replicate SNPs that are reported to be associated with AF in two large study samples of European descent.We searched PubMed for studies reporting associations between SNPs and AF published before July 1, 2007. SNPs were genotyped in two i...     »
Zeitschriftentitel:
Heart Rhythm
Jahr:
2011
Band / Volume:
8
Heft / Issue:
3
Seitenangaben Beitrag:
403-9
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.hrthm.2010.11.003
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21056700
Print-ISSN:
1547-5271
TUM Einrichtung:
Institut für Humangenetik
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