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Title:

Genes predict village of origin in rural Europe.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
O'Dushlaine, C; McQuillan, R; Weale, ME; Crouch, DJ; Johansson, Å; Aulchenko, Y; Franklin, CS; Pola?ek, O; Fuchsberger, C; Corvin, A; Hicks, AA; Vitart, V; Hayward, C; Wild, SH; Meitinger, T; van Duijn, CM; Gyllensten, U; Wright, AF; Campbell, H; Pramstaller, PP; Rudan, I; Wilson, JF
Abstract:
The genetic structure of human populations is important in population genetics, forensics and medicine. Using genome-wide scans and individuals with all four grandparents born in the same settlement, we here demonstrate remarkable geographical structure across 8-30 km in three different parts of rural Europe. After excluding close kin and inbreeding, village of origin could still be predicted correctly on the basis of genetic data for 89-100% of individuals.
Journal title abbreviation:
Eur J Hum Genet
Year:
2010
Journal volume:
18
Journal issue:
11
Pages contribution:
1269-70
Language:
eng
Fulltext / DOI:
doi:10.1038/ejhg.2010.92
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20571506
Print-ISSN:
1018-4813
TUM Institution:
Institut für Humangenetik
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