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Titel:

A double-blind, randomized study on prevention and existence of a rebound phenomenon of platelets after cessation of clopidogrel treatment.

Dokumenttyp:
Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Article
Autor(en):
Sibbing, D; Stegherr, J; Braun, S; Mehilli, J; Schulz, S; Seyfarth, M; Kastrati, A; von Beckerath, N; Schömig, A
Abstract:
The goal of this study was to assess whether a platelet rebound exists and whether it can be attenuated by clopidogrel tapering.Clinical studies have reported a clustering of thrombotic events after stopping clopidogrel treatment. The hypothesis of a rebound phenomenon of platelets has been declared causative, but its existence has never been confirmed. Tapering of clopidogrel over a certain period of time before stopping the drug completely might provide a way to attenuate this supposed phenome...     »
Zeitschriftentitel:
J Am Coll Cardiol
Jahr:
2010
Band / Volume:
55
Heft / Issue:
6
Seitenangaben Beitrag:
558-65
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.jacc.2009.09.038
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20152561
Print-ISSN:
0735-1097
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie); Institut für Laboratoriumsmedizin (keine SAP-Zuordnung!)
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