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Titel:

Head circumference, atrophy, and cognition: implications for brain reserve in Alzheimer disease.

Dokumenttyp:
Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Article
Autor(en):
Perneczky, R; Wagenpfeil, S; Lunetta, KL; Cupples, LA; Green, RC; Decarli, C; Farrer, LA; Kurz, A
Abstract:
BACKGROUND: Clinical and epidemiologic studies suggest that patients with Alzheimer disease (AD) with larger head circumference have better cognitive performance at the same level of brain pathology than subjects with smaller head circumference. METHODS: A total of 270 patients with AD participating in the Multi-Institutional Research in Alzheimer's Genetic Epidemiology (MIRAGE) study underwent cognitive testing, APOE genotyping, and MRI of the brain in a cross-sectional study. Linear regression...     »
Zeitschriftentitel:
Neurology
Jahr:
2010
Band / Volume:
75
Heft / Issue:
2
Seitenangaben Beitrag:
137-42
Sprache:
eng
Volltext / DOI:
doi:10.1212/WNL.0b013e3181e7ca97
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20625166
Print-ISSN:
0028-3878
TUM Einrichtung:
Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Psychiatrie und Psychotherapie
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