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Titel:

Standardized antigen preparation to achieve comparability of anti-beta2-glycoprotein I assays.

Dokumenttyp:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Müller, C; Schlichtiger, A; Balling, G; Steigerwald, U; Luppa, PB; Thaler, M
Abstract:
The Sydney classification for diagnosis of the antiphospholipid syndrome (APS) first introduced the determination of anti-beta2-glycoprotein I (anti-beta2-GPI)-antibodies in serum as laboratory criteria. In this context, widely differing results of anti-beta2-GPI assays are a concerning issue. Considerable efforts have been made to optimize ELISAs, however little attention was hitherto spent to the antigen preparation. We evaluated the influence of different beta2-GPI preparations on the ability...     »
Zeitschriftentitel:
Thromb Res
Jahr:
2010
Band / Volume:
126
Heft / Issue:
2
Seitenangaben Beitrag:
e102-9
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.thromres.2010.05.022
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20659619
Print-ISSN:
0049-3848
TUM Einrichtung:
Institut für Klinische Chemie und Pathobiochemie
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