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Title:

Standardized antigen preparation to achieve comparability of anti-beta2-glycoprotein I assays.

Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Müller, C; Schlichtiger, A; Balling, G; Steigerwald, U; Luppa, PB; Thaler, M
Abstract:
The Sydney classification for diagnosis of the antiphospholipid syndrome (APS) first introduced the determination of anti-beta2-glycoprotein I (anti-beta2-GPI)-antibodies in serum as laboratory criteria. In this context, widely differing results of anti-beta2-GPI assays are a concerning issue. Considerable efforts have been made to optimize ELISAs, however little attention was hitherto spent to the antigen preparation. We evaluated the influence of different beta2-GPI preparations on the ability...     »
Journal title abbreviation:
Thromb Res
Year:
2010
Journal volume:
126
Journal issue:
2
Pages contribution:
e102-9
Language:
eng
Fulltext / DOI:
doi:10.1016/j.thromres.2010.05.022
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20659619
Print-ISSN:
0049-3848
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie
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