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Title:

Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages.

Document type:
Journal Article; Review
Author(s):
Gillen, S; Schuster, T; Meyer Zum Büschenfelde, C; Friess, H; Kleeff, J
Abstract:
BACKGROUND: Pancreatic cancer has an extremely poor prognosis and prolonged survival is achieved only by resection with macroscopic tumor clearance. There is a strong rationale for a neoadjuvant approach, since a relevant percentage of pancreatic cancer patients present with non-metastatic but locally advanced disease and microscopic incomplete resections are common. The objective of the present analysis was to systematically review studies concerning the effects of neoadjuvant therapy on tumor...     »
Journal title abbreviation:
PLoS Med
Year:
2010
Journal volume:
7
Journal issue:
4
Pages contribution:
e1000267
Language:
eng
Fulltext / DOI:
doi:10.1371/journal.pmed.1000267
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20422030
Print-ISSN:
1549-1277
TUM Institution:
Chirurgische Klinik und Poliklinik; III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Medizinische Statistik und Epidemiologie
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