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Titel:

Synthesis, biological evaluation and radiolabelling by 18F-fluoroarylation of a dopamine D3-selective ligand as prospective imaging probe for PET.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Höfling, SB; Maschauer, S; Hübner, H; Gmeiner, P; Wester, HJ; Prante, O; Heinrich, MR
Abstract:
Radical (18)F-fluoroarylation with fluorine-18-labelled arenediazonium chlorides has been successfully applied to the radiochemical synthesis of the dopamine D(3)-selective ligand SH 317 ([(18)F]8). SH 317 has been evaluated as a new PET ligand candidate by in vivo experiments.
Zeitschriftentitel:
Bioorg Med Chem Lett
Jahr:
2010
Band / Volume:
20
Heft / Issue:
23
Seitenangaben Beitrag:
6933-7
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.bmcl.2010.09.142
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21030255
Print-ISSN:
0960-894X
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
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