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Title:

Tumor microenvironment and progression of pancreatic cancer.

Document type:
Journal Article
Author(s):
Erkan, M; Reiser-Erkan, C; Michalski, CW; Kleeff, J
Abstract:
Pancreatic ductal adenocarcinoma is characterized by « tumor desmoplasia », a remarkable increase in connective tissue that penetrates and envelopes the neoplasm. It is becoming clear that this desmoplastic microenvironment of pancreatic cancer--which is forming approximately eighty percent of the tumor mass--is not a passive scaffold for the tumor cells but an active player in carcinogenesis. Several chemotherapeutic agents and novel molecular targeted therapies against epithelial tumor cells--...     »
Journal title abbreviation:
Exp Oncol
Year:
2010
Journal volume:
32
Journal issue:
3
Pages contribution:
128-31
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21403605
Print-ISSN:
1812-9269
TUM Institution:
Chirurgische Klinik und Poliklinik
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