Extensive studies in rodents have associated the threats of pain, predators, and aggressive conspecifics with distinct neural circuits in subregions of the amygdala, hypothalamus, and periaqueductal gray. In this fMRI study we investigated 45 healthy female subjects during classical aversive conditioning. Our results demonstrate distinct brain activations in the amygdala and hypothalamus for the threats of pain, predators and aggressive conspecifics, suggesting that threat type specific circuits identified in rodents might be conserved in the human brain.
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Extensive studies in rodents have associated the threats of pain, predators, and aggressive conspecifics with distinct neural circuits in subregions of the amygdala, hypothalamus, and periaqueductal gray. In this fMRI study we investigated 45 healthy female subjects during classical aversive conditioning. Our results demonstrate distinct brain activations in the amygdala and hypothalamus for the threats of pain, predators and aggressive conspecifics, suggesting that threat type specific circuits...
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