Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial

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Title:: Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial
Document type:: Zeitschriftenaufsatz
Author(s):: Levin, Johannes; Sing, Nand; Melbourne, Sue; Morgan, Amber; Mariner, Carla; Spillantini, Maria Grazia; Wegrzynowicz, Michal; Dalley, Jeffrey W.; Langer, Simon; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Schmidt, Felix; Weckbecker, Daniel; Prager, Kai; Matthias, Torsten; Giese, Armin
Journal title:: eBioMedicine
Year:: 2022
Journal volume:: 80
Pages contribution:: 104021
Fulltext / DOI:: doi:10.1016/j.ebiom.2022.104021
Publisher:: Elsevier BV
E-ISSN:: 2352-3964
Date of publication:: 01.06.2022
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