Polygenic risk scores indicate extreme ages at onset of breast cancer in female BRCA1/2 pathogenic variant carriers

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Title:: Polygenic risk scores indicate extreme ages at onset of breast cancer in female BRCA1/2 pathogenic variant carriers
Document type:: Zeitschriftenaufsatz
Author(s):: Borde, Julika ; Laitman, Yael ; Blümcke, Britta ; Niederacher, Dieter ; Weber-Lassalle, Konstantin ; Sutter, Christian ; Rump, Andreas ; Arnold, Norbert ; Wang-Gohrke, Shan ; Horváth, Judit ; Gehrig, Andrea ; Schmidt, Gunnar ; Dutrannoy, Véronique ; Ramser, Juliane ; Hentschel, Julia ; Meindl, Alfons ; Schroeder, Christopher ; Wappenschmidt, Barbara ; Engel, Christoph ; Kuchenbaecker, Karoline ; Schmutzler, Rita K. ; Friedman, Eitan ; Hahnen, Eric ; Ernst, Corinna
Keywords:: Research ; Breast cancer ; Polygenic risk score ; PRS ; Risk assessment ; ; Medical and Health Sciences
Journal title:: BMC Cancer
Year:: 2022
Journal volume:: 22
Journal issue:: 1
Fulltext / DOI:: doi:10.1186/s12885-022-09780-1
Publisher:: BioMed Central
E-ISSN:: 1471-2407
Date of publication:: 27.06.2022
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