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- Title:
Screening Privileged Alkyl Guanidinium Motifs underHost-Mimicking Conditions Reveals a Novel Antibiotic with an UnconventionalMode of Action
- Document type:
- Zeitschriftenaufsatz
- Author(s):
- Schum, Dominik ; Elsen, Franziska A. V. ; Ruddell, Stuart ; Schorpp, Kenji ; Junca, Howard ; Mu sken, Mathias ; Chen, Shu-Yu ; Fiedler, Michaela K. ; Pickl, Thomas ; Pieper, Dietmar H. ; Hadian, Kamyar ; Zacharias, Martin ; Sieber, Stephan A.
- Keywords:
- Article ; antibiotic development ; high-throughput screen ; host-mimicking conditions ; guanidinium compounds ; proteomics ; target identification ; signal peptidase
- Journal title:
- JACS Au
- Year:
- 2024
- Journal volume:
- 4
- Journal issue:
- 8
- Pages contribution:
- 3125-3134
- Fulltext / DOI:
- doi:10.1021/jacsau.4c00449
- Publisher:
- American Chemical Society
- E-ISSN:
- 2691-3704
- Date of publication:
- 16.07.2024
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