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Title:

Patient-derived organoid biobank identifies epigenetic dysregulation of intestinal epithelial MHC-I as a novel mechanism in severe Crohn's Disease

Document type:
Zeitschriftenaufsatz
Author(s):
Dennison, Thomas W ; Edgar, Rachel D ; Payne, Felicity ; Nayak, Komal M ; Ross, Alexander D. B. ; Cenier, Aurelie ; Glemas, Claire ; Giachero, Federica ; Foster, April R ; Harris, Rebecca ; Kraiczy, Judith ; Salvestrini, Camilla ; Stavrou, Georgia ; Torrente, Franco ; Brook, Kimberley ; Trayers, Claire ; Elmentaite, Rasa ; Youssef, Gehad ; Tél, Bálint ; Winton, Douglas James ; Skoufou-Papoutsaki, Nefeli ; Adler, Sam ; Bufler, Philip ; Azabdaftari, Aline ; Jenke, Andreas ;...     »
Keywords:
Inflammatory bowel disease ; METHYLATION ; CROHN'S DISEASE ; INTESTINAL EPITHELIUM ; INFLAMMATORY BOWEL DISEASE
Journal title:
Gut
Year:
2024
Fulltext / DOI:
doi:10.1136/gutjnl-2024-332043
Publisher:
BMJ Publishing Group Ltd and British Society of Gastroenterology
E-ISSN:
0017-5749 ; 1468-3288
Date of publication:
10.06.2024
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