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Title:

In Silico and In Vitro Study towards the Rational Design of 4,4 -Disarylbisthiazoles as a Selective α-Synucleinopathy Biomarker

Document type:
Zeitschriftenaufsatz
Author(s):
Uzuegbunam, Bright C. ; Li, Junhao ; Paslawski, Wojciech ; Weber, Wolfgang ; Svenningsson, Per ; Ågren, Hans ; Hooshyar Yousefi, Behrooz
Keywords:
Article ; α-synuclein aggregates ; 4,4 -diarylbisthiazole ; binding affinity ; Hantzsch thiazole synthesis ; lipophilicity ; O-fluoroethylation ; O-fluoroPEGylation ; O-methylation
Journal title:
International Journal of Molecular Sciences
Year:
2023
Journal volume:
24
Journal issue:
22
Fulltext / DOI:
doi:10.3390/ijms242216445
Publisher:
MDPI
E-ISSN:
1422-0067
Date of publication:
17.11.2023
CC license:
by, https://creativecommons.org/licenses/by/4.0
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