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Title:

Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency

Document type:
Zeitschriftenaufsatz
Author(s):
Reifschneider, Anika ; Robinson, Sophie ; van Lengerich, Bettina ; Gnörich, Johannes ; Logan, Todd ; Heindl, Steffanie ; Vogt, Miriam A ; Weidinger, Endy ; Riedl, Lina ; Wind, Karin ; Zatcepin, Artem ; Pesämaa, Ida ; Haberl, Sophie ; Nuscher, Brigitte ; Kleinberger, Gernot ; Klimmt, Julien ; Götzl, Julia K ; Liesz, Arthur ; Bürger, Katharina ; Brendel, Matthias ; Levin, Johannes ; Diehl-Schmid, Janine ; Suh, Jung ; Di Paolo, Gilbert ; Lewcock, Joseph W ; Monroe, Kathryn...     »
Keywords:
EMBO19 ; EMBO27 ; Article ; Articles ; frontotemporal lobar degeneration ; lysosomes ; microglia ; neurodegeneration ; progranulin
Journal title:
The EMBO Journal
Year:
2022
Journal volume:
41
Journal issue:
4
Fulltext / DOI:
doi:10.15252/embj.2021109108
E-ISSN:
0261-4189 ; 1460-2075
Date of publication:
12.01.2022
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