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Document type:
Observational Study; Journal Article
Keppler-Hafkemeyer, Andrea; Greil, Christine; Wratil, Paul R; Shoumariyeh, Khalid; Stern, Marcel; Hafkemeyer, Annika; Ashok, Driti; Hollaus, Alexandra; Lupoli, Gaia; Priller, Alina; Bischof, Marie L; Ihorst, Gabriele; Engelhardt, Monika; Marks, Reinhard; Finke, Jürgen; Bertrand, Hannah; Dächert, Christopher; Muenchhoff, Maximilian; Badell, Irina; Emmerich, Florian; Halder, Hridi; Spaeth, Patricia M; Knolle, Percy A; Protzer, Ulrike; von Bergwelt-Baildon, Michael; Duyster, Justus; Hartmann, Tanja...     »
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.
Individuals with hematologic malignancies are at increased risk for severe coronavirus disease 2019 (COVID-19), yet profound analyses of COVID-19 vaccine-induced immunity are scarce. Here we present an observational study with expanded methodological analysis of a longitudinal, primarily BNT162b2 mRNA-vaccinated cohort of 60 infection-naive individuals with B cell lymphomas and multiple myeloma. We show that many of these individuals, despite markedly lower anti-spike IgG titers, rapidly develop...     »
Journal title abbreviation:
Nat. Cancer
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TUM Institution:
608; Institut für Experimentelle Onkologie und Therapieforschung; Institut für Virologie (Prof. Protzer); Roman Herzog Comprehensive Cancer Center