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- Title:
A trans locus causes a ribosomopathy in hypertrophic hearts that affects mRNA translation in a protein length-dependent fashion
- Document type:
- Zeitschriftenaufsatz
- Author(s):
- Witte, Franziska ; Ruiz-Orera, Jorge ; Mattioli, Camilla Ciolli ; Blachut, Susanne ; Adami, Eleonora ; Schulz, Jana Felicitas ; Schneider-Lunitz, Valentin ; Hummel, Oliver ; Patone, Giannino ; Mücke, Michael Benedikt ; Šilhavý, Jan ; Heinig, Matthias ; Bottolo, Leonardo ; Sanchis, Daniel ; Vingron, Martin ; Chekulaeva, Marina ; Pravenec, Michal ; Hubner, Norbert ; van Heesch, Sebastiaan
- Keywords:
- Research ; Genetic variation ; Translational efficiency ; Ribosome profiling ; Cardiac hypertrophy ; Ribosome biogenesis ; Ribosomopathy ; Complex disease ; Spontaneously hypertensive rats (SHR) ; HXB/BXH rat recombinant inbred panel
- Journal title:
- Genome Biology
- Year:
- 2021
- Journal volume:
- 22
- Journal issue:
- 1
- Fulltext / DOI:
- doi:10.1186/s13059-021-02397-w
- Publisher:
- BioMed Central
- E-ISSN:
- 1474-760X
- Date of publication:
- 28.06.2021
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