Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals

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Titel:: Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals
Dokumenttyp:: Zeitschriftenaufsatz
Autor(en):: Lv, You ; Zheng, Shan ; Goldenzweig, Adi ; Liu, Fengjiang ; Gao, Yan ; Yang, Xiuna ; Kandale, Ajit ; McGeary, Ross P. ; Williams, Simon ; Kobe, Bostjan ; Schembri, Mark A. ; Landsberg, Michael J. ; Wu, Bin ; Brück, Thomas B. ; Sieber, Volker ; Boden, Mikael ; Rao, Zihe ; Fleishman, Sarel J. ; Schenk, Gerhard ; Guddat, Luke W.
Stichworte:: Article ; cell-free enzyme cascades ; biomanufacturing ; enzyme stability ; protein design ; PROSS ; branched chain amino acid biosynthesis ; ketol-acid reductoisomerase
Zeitschriftentitel:: Applied Biosciences
Jahr:: 2022
Band / Volume:: 1
Heft / Issue:: 2
Seitenangaben Beitrag:: 163-178
Volltext / DOI:: doi:10.3390/applbiosci1020011
Verlag / Institution:: MDPI
E-ISSN:: 2813-0464
Publikationsdatum:: 10.08.2022
CC-Lizenz:: by, https://creativecommons.org/licenses/by/4.0

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