The enthesis is the attachment of tendons/ligaments to bones. The healing capacity of the enthesis is low. Thus, finding a repair system poses a challenge to therapy and research. This study aims to evaluate the in vivo healing capacity of biphasic silk-fibroin scaffolds in a rat patella enthesis defect model. Silk-fibroin scaffolds supported cell immigration and the regeneration of an organized extracellular matrix. The findings show that biphasic silk-fibroin scaffolds are promising candidates for regeneration of the enthesis and can support further research in this field.
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The enthesis is the attachment of tendons/ligaments to bones. The healing capacity of the enthesis is low. Thus, finding a repair system poses a challenge to therapy and research. This study aims to evaluate the in vivo healing capacity of biphasic silk-fibroin scaffolds in a rat patella enthesis defect model. Silk-fibroin scaffolds supported cell immigration and the regeneration of an organized extracellular matrix. The findings show that biphasic silk-fibroin scaffolds are promising candidates...
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