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- Title:
Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM+ and CD90+ Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model
- Document type:
- Zeitschriftenaufsatz
- Author(s):
- Moustafa, Mohamed ; Dähling, Katarzyna-Krystyna ; Günther, Armin ; Riebandt, Leonie ; Smit, Daniel J. ; Riecken, Kristoffer ; Schröder, Carina ; Zhuang, Ruimeng ; Krech, Till ; Kriegs, Malte ; Fehse, Boris ; Izbicki, Jakob R. ; Fischer, Lutz ; Nashan, Björn ; Li, Jun ; Jücker, Manfred
- Keywords:
- Article ; hepatocellular carcinoma ; AKT ; mTOR ; combined treatment ; tumor spheroids ; orthotopic mouse model ; treatment resistance ; EpCAM ; CD90 ; CSC
- Journal title:
- Cancers
- Year:
- 2022
- Journal volume:
- 14
- Journal issue:
- 8
- Fulltext / DOI:
- doi:10.3390/cancers14081882
- Publisher:
- MDPI
- E-ISSN:
- 2072-6694
- Date of publication:
- 08.04.2022
- CC license:
- by, https://creativecommons.org/licenses/by/4.0
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