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Titel:

Current research approaches in downstream processing of pharmaceutically relevant proteins

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Schwaminger SP, Zimmermann I, Berensmeier S
Abstract:
Biopharmaceuticals and their production are on the rise. They are needed to treat and to prevent multiple diseases. Therefore, an urgent need for process intensification in downstream processing (DSP) has been identified to produce biopharmaceuticals more efficiently. The DSP currently accounts for the majority of production costs of pharmaceutically relevant proteins. This short review gathers essential research over the past 3 years that addresses novel solutions to overcome this bottleneck. T...     »
Stichworte:
Downstream processing (DSP); process intensification; current opinion; protein purification; chromatography; magnetic separation; precipitation; filtration; aqueous two-phase systems
Zeitschriftentitel:
Current Opinion in Biotechnology
Jahr:
2022
Band / Volume:
77
Jahr / Monat:
2022-10
Monat:
Oct
Seitenangaben Beitrag:
102768
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1016/j.copbio.2022.102768
Verlag / Institution:
Elsevier BV
Print-ISSN:
0958-1669
E-ISSN:
0958-1669
Impact Factor:
10.279
Publikationsdatum:
01.10.2022
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