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Titel:

Contamination with Black Carbon Nanoparticles Alters the Selective Permeability of Mucin Hydrogels: Implications for Molecular Transport across Mucosal Barriers

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Marczynski, Matthias; Lutz, Theresa M.; Schlatterer, Rebecca; Henkel, Manuel; Balzer, Bizan N.; Lieleg, Oliver
Abstract:
Mucus is a complex hydrogel biomaterial whose composition is regulated meticulously to ensure that its important function as a selective barrier is maintained. As part of this function, mucus regulates the uptake of molecules from the gastrointestinal lumen into the body. Yet, those hydrogels are continuously challenged with environmental pollutants such as black carbon nanoparticles (NPs), and there is growing evidence that these contaminants can compromise the functionality of mucus. Here, we...     »
Stichworte:
electrostatic interactions; mucus; nanoparticles; particulate matter; partitioning; translocation
Dewey Dezimalklassifikation:
500 Naturwissenschaften
Zeitschriftentitel:
ACS Applied Nano Materials
Jahr:
2022
Band / Volume:
5
Heft / Issue:
11
Seitenangaben Beitrag:
16955-16970
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1021/acsanm.2c03887
WWW:
https://www.scopus.com/record/display.uri?eid=2-s2.0-85141969609&origin=resultslist&zone=contextBox
Verlag / Institution:
American Chemical Society (ACS)
E-ISSN:
2574-09702574-0970
Publikationsdatum:
11.11.2022
TUM Einrichtung:
Fachgebiet für Biomechanik, MW
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