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Titel:

Immune‐Modulating Mucin Hydrogel Microdroplets for the Encapsulation of Cell and Microtissue

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Yan, Hongji; Melin, Marcus; Jiang, Kun; Trossbach, Martin; Badadamath, Bharathesh; Langer, Krzysztof; Winkeljann, Benjamin; Lieleg, Oliver; Hong, Jaan; Joensson, Haakan N.; Crouzier, Thomas
Abstract:
Immune-modulating biomaterials used to encapsulate cells and microtissue transplants can be engineered to dampen the immune reaction and increase treatment efficacy. Mucin-derived materials have gained attention for their ability to modulate macrophage and dendritic cell activity, and to trigger mild foreign body response when implanted in vivo. In this study, the potential of mucin hydrogels (Muc-gels) as cell-encapsulating materials is investigated. When placed in contact with blood, Muc-gels...     »
Stichworte:
complement system; insulin; microdroplets; microtissues; mucin hydrogels
Dewey Dezimalklassifikation:
500 Naturwissenschaften
Zeitschriftentitel:
Advanced Functional Materials
Jahr:
2021
Band / Volume:
31
Heft / Issue:
42
Seitenangaben Beitrag:
2105967
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1002/adfm.202105967
Verlag / Institution:
Wiley
E-ISSN:
1616-301X1616-3028
Publikationsdatum:
21.07.2021
TUM Einrichtung:
Fachgebiet für Biomechanik, MW
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