Benutzer: Gast  Login
Titel:

Structural Alterations of Mucins Are Associated with Losses in Functionality

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Marczynski, Matthias; Jiang, Kun; Blakeley, Matthew; Srivastava, Vaibhav; Vilaplana, Francisco; Crouzier, Thomas; Lieleg, Oliver
Abstract:
Commercial mucin glycoproteins are routinely used as a model to investigate the broad range of important functions mucins fulfill in our bodies, including lubrication, protection against hostile germs, and the accommodation of a healthy microbiome. Moreover, purified mucins are increasingly selected as building blocks for multifunctional materials, i.e., as components of hydrogels or coatings. By performing a detailed side-by-side comparison of commercially available and lab-purified variants of...     »
Stichworte:
Purification; Building blockes; Macroscopic levels; Medical products; Multi-functional materials; Porcine gastric mucins; Structural alterations; Structural feature; Structural motifs; Glycoproteins
Dewey Dezimalklassifikation:
500 Naturwissenschaften
Zeitschriftentitel:
Biomacromolecules
Jahr:
2021
Band / Volume:
22
Heft / Issue:
4
Seitenangaben Beitrag:
1600-1613
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1021/acs.biomac.1c00073
WWW:
https://www.scopus.com/record/display.uri?eid=2-s2.0-85104209432&origin=resultslist&sort=plf-f&src=s&st1=Lieleg&st2=Oliver&nlo=1&nlr=20&nls=count-f&sid=5d74543a2ec2798c9fe15407ca5d295d&sot=anl&sdt=aut&sl=35&s=AU-ID("Lieleg,+Oliver"+22835524400)&relpos=3&citeCnt=2
Verlag / Institution:
American Chemical Society (ACS)
E-ISSN:
1525-77971526-4602
Publikationsdatum:
22.03.2021
TUM Einrichtung:
Professur für Biomechanik
 BibTeX