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Title:

A novel modelling and simulation approach for the hindered mobility of charged particles in biological hydrogels

Document type:
Zeitschriftenaufsatz
Author(s):
Grill, Maximilian J.; Eichinger, Jonas F.; Koban, Jonas; Meier, Christoph; Lieleg, Oliver; Wall, Wolfgang A.
Abstract:
This article presents a novel computational model to study the selective filtering of biological hydrogels due to the surface charge and size of diffusing particles. It is the first model that includes the random three-dimensional fibre orientation and connectivity of the biopolymer network and that accounts for elastic deformations of the fibres by means of beam theory. As a key component of the model, novel formulations are proposed both for the electrostatic and repulsive steric interactions...     »
Keywords:
beam theory; biological hydrogels; deformable fibre network; electrostatic interaction; finite-element method; hindered particle diffusion
Dewey Decimal Classification:
500 Naturwissenschaften
Journal title:
Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
Year:
2021
Journal volume:
477
Journal issue:
2249
Pages contribution:
20210039
Covered by:
Scopus
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1098/rspa.2021.0039
WWW:
https://www.scopus.com/record/display.uri?eid=2-s2.0-85107673908&origin=resultslist&sort=plf-f&src=s&st1=Lieleg&st2=Oliver&nlo=1&nlr=20&nls=count-f&sid=5d74543a2ec2798c9fe15407ca5d295d&sot=anl&sdt=aut&sl=35&s=AU-ID("Lieleg,+Oliver"+22835524400)&relpos=2&citeCnt=1
Publisher:
The Royal Society
E-ISSN:
1364-50211471-2946
Date of publication:
01.05.2021
TUM Institution:
Professur für Biomechanik
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