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Titel:

Confidence interval estimation for the changepoint of treatment stratification in the presence of a qualitative covariate-treatment interaction.

Dokumenttyp:
Journal Article
Autor(en):
Haller, Bernhard; Mansmann, Ulrich; Dobler, Dennis; Ulm, Kurt; Hapfelmeier, Alexander
Abstract:
The goal in stratified medicine is to administer the "best" treatment to a patient. Not all patients might benefit from the same treatment; the choice of best treatment can depend on certain patient characteristics. In this article, it is assumed that a time-to-event outcome is considered as a patient-relevant outcome and a qualitative interaction between a continuous covariate and treatment exists, ie, that patients with different values of one specific covariate should be treated differently....     »
Zeitschriftentitel:
Stat Med
Jahr:
2020
Band / Volume:
39
Heft / Issue:
1
Seitenangaben Beitrag:
70-96
Volltext / DOI:
doi:10.1002/sim.8404
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31701549
Print-ISSN:
0277-6715
TUM Einrichtung:
Institut für Medizinische Statistik und Epidemiologie
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