Age- and gender-related variations of cervical muscle composition using chemical shift encoding-based water-fat MRI.

Burian, Egon; Franz, Daniela; Greve, Tobias; Dieckmeyer, Michael; Holzapfel, Christina; Drabsch, Theresa; Sollmann, Nico; Probst, Monika; Kirschke, Jan S; Rummeny, Ernst J; Zimmer, Claus; Hauner, Hans; Karampinos, Dimitrios C; Baum, Thomas

doi:10.1016/j.ejrad.2020.108904

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journal article

Title:: Age- and gender-related variations of cervical muscle composition using chemical shift encoding-based water-fat MRI.
Document type:: Journal Article
Author(s):: Burian, Egon; Franz, Daniela; Greve, Tobias; Dieckmeyer, Michael; Holzapfel, Christina; Drabsch, Theresa; Sollmann, Nico; Probst, Monika; Kirschke, Jan S; Rummeny, Ernst J; Zimmer, Claus; Hauner, Hans; Karampinos, Dimitrios C; Baum, Thomas
Abstract:: PURPOSE: To understand fat distribution patterns and ectopic fat deposition in healthy adults and to provide normative data, encompassing the borders of physiological regional muscle composition. For this purpose chemical shift encoding-based water-fat Magnetic Resonance Imaging (MRI) was used for proton density fat fraction (PDFF) calculations. MATERIAL AND METHODS: 91 volunteers were enrolled (male: n = 28, age = 36.6 ± 11.4 years; female: n = 63, age = 38.5 ± 15.1 years). PDFF values combined for the multifidus, semispinalis and spinalis cervicis muscles at the level of the 3rd cervical vertebral body (C3), the 5th cervical vertebral body (C5) and the first thoracic vertebral body (Th1) were extracted. RESULTS: The paraspinal musculature at C3 (14.8 ± 10.1 % vs. 19.2 ± 11.0 %; p = 0.029) and Th1 (13.8 ± 7.0 % vs 17.7 ± 7.4 %; p = 0.011) showed significantly lower PDFF values in men compared to women. Partial correlation testing with BMI as control variable revealed highly significant correlations between the paraspinal musculature PDFF at C3 (men: r = 0.504, p = 0.007; women: r = 0.279, p = 0.028), C5 (men: r = 0.450, p = 0.019; women: r = 0.347, p = 0.006) and Th1 (men: r = 0.652, p < 0.0001; women: r = 0.443, p < 0.0001) with age in both genders. CONCLUSION: The present data suggest gender and age-specific fat deposition patterns of the cervical and the upper cervicothoracic paraspinal muscles and may provide reference values for pathology detection.
Journal title abbreviation:: Eur J Radiol
Year:: 2020
Journal volume:: 125
Fulltext / DOI:: doi:10.1016/j.ejrad.2020.108904
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/32088656
Print-ISSN:: 0720-048X
TUM Institution:: Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin; Fachgebiet Neuroradiologie (Prof. Zimmer)
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mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Klinik für Ernährungsmedizin (Prof. Hauner)2020

mediaTUM Gesamtbestand Hochschulbibliographie 2020 Fakultäten Medizin Institut für Radiologie

mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Institut für Diagnostische und Interventionelle Radiologie (Prof. Makowski)Abteilung für Diagnostische und Interventionelle Neuroradiologie (Prof. Zimmer)Professur für Neuroradiologie (Prof. Zimmer)2020

mediaTUM Gesamtbestand Hochschulbibliographie 2020 Fakultäten Medizin Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin

mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Institut für Diagnostische und Interventionelle Radiologie (Prof. Makowski)2020