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Title:

Synergistic antitumor effects of transarterial viroembolization for multifocal hepatocellular carcinoma in rats.

Document type:
Journal Article
Author(s):
Altomonte, J; Braren, R; Schulz, S; Marozin, S; Rummeny, EJ; Schmid, RM; Ebert, O
Abstract:
Oncolytic virotherapy is a promising strategy for safe and effective treatment of malignancy. We have reported previously that recombinant vesicular stomatitis virus (VSV) vectors are effective oncolytic agents that can be safely administered via the hepatic artery in immunocompetent rats to treat multifocal hepatocellular carcinoma (HCC), resulting in tumor necrosis and prolonged survival. Though the results were encouraging, complete tumor regression was not observed, which led us to explore a...     »
Journal title abbreviation:
Hepatology
Year:
2008
Journal volume:
48
Journal issue:
6
Pages contribution:
1864-73
Language:
eng
Fulltext / DOI:
doi:10.1002/hep.22546
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19003878
Print-ISSN:
0270-9139
TUM Institution:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Allgemeine Pathologie und Pathologische Anatomie
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