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Titel:

Rapid leukocyte migration by integrin-independent flowing and squeezing.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Lämmermann, T; Bader, BL; Monkley, SJ; Worbs, T; Wedlich-Söldner, R; Hirsch, K; Keller, M; Förster, R; Critchley, DR; Fässler, R; Sixt, M
Abstract:
All metazoan cells carry transmembrane receptors of the integrin family, which couple the contractile force of the actomyosin cytoskeleton to the extracellular environment. In agreement with this principle, rapidly migrating leukocytes use integrin-mediated adhesion when moving over two-dimensional surfaces. As migration on two-dimensional substrates naturally overemphasizes the role of adhesion, the contribution of integrins during three-dimensional movement of leukocytes within tissues has rem...     »
Zeitschriftentitel:
Nature
Jahr:
2008
Band / Volume:
453
Heft / Issue:
7191
Seitenangaben Beitrag:
51-5
Sprache:
eng
Volltext / DOI:
doi:10.1038/nature06887
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18451854
Print-ISSN:
0028-0836
TUM Einrichtung:
Else Kröner-Fresenius-Zentrum für Ernährungsmedizin - Klinik für Ernährungsmedizin
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