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Document type:
Journal Article 
Author(s):
Gilles, S; Mariani, V; Bryce, M; Mueller, MJ; Ring, J; Behrendt, H; Jakob, T; Traidl-Hoffmann, C 
Title:
Pollen allergens do not come alone: pollen associated lipid mediators (PALMS) shift the human immune systems towards a T(H)2-dominated response. 
Abstract:
Pollen allergy is characterized by a T(H)2-biased immune response to pollen-derived allergens. However, pollen-exposed epithelia do not encounter pure allergen but rather a plethora of protein and non-protein substances. We demonstrated that pollen liberate lipids with chemical and functional similarities to leukotriens and prostaglandins--the pollen associated lipid mediators (PALMs). To date, two main groups of PALMs have been characterized: The immunostimulatory PALMs activating innate immune...    »
 
Journal title abbreviation:
Allergy Asthma Clin Immunol 
Year:
2009 
Journal volume:
Journal issue:
Pages contribution:
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1710-1484 
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)