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Titel:

Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease.

Dokumenttyp:
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Article
Autor(en):
Rodriguez, E; Baurecht, H; Herberich, E; Wagenpfeil, S; Brown, SJ; Cordell, HJ; Irvine, AD; Weidinger, S
Abstract:
BACKGROUND: The discovery of filaggrin (FLG) null mutations as a major risk factor for eczema represents a milestone toward the understanding of an important mechanism in this complex disease. However, published studies demonstrate differences concerning design and effect size, and conflicting results for asthma have been reported. OBJECTIVES: We sought to provide a more accurate estimate of FLG effect sizes and to better refine FLG risk profiles within the broad and inclusive eczema diagnosis....     »
Zeitschriftentitel:
J Allergy Clin Immunol
Jahr:
2009
Band / Volume:
123
Heft / Issue:
6
Seitenangaben Beitrag:
1361-70.e7
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.jaci.2009.03.036
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19501237
Print-ISSN:
0091-6749
TUM Einrichtung:
Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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