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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Frei, E; Hofmann, F; Wegener, JW 
Title:
Phospholipase C mediated Ca2+ signals in murine urinary bladder smooth muscle. 
Abstract:
Muscarinic stimulation of urinary bladder induces contraction via an increase in intracellular Ca(2+) concentration that results from Ca(2+) influx through Ca(2+) channels and/or IP(3)-mediated Ca(2+) release controlled by phospholipase C (PLC) signalling. The significance of PLC/IP(3) signalling in this cascade has recently been questioned because PLC inhibitors were without effect on carbachol-induced contractions in detrusor muscle strips. However, PLC/IP(3)-mediated Ca(2+) release was clearl...    »
 
Journal title abbreviation:
Eur J Pharmacol 
Year:
2009 
Journal volume:
610 
Journal issue:
1-3 
Pages contribution:
106-9 
Language:
eng 
Print-ISSN:
0014-2999 
TUM Institution:
Institut für Pharmakologie und Toxikologie 
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