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Titel:

Evaluation of the novel myocardial perfusion positron-emission tomography tracer 18F-BMS-747158-02: comparison to 13N-ammonia and validation with microspheres in a pig model.

Dokumenttyp:
Comparative Study; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Nekolla, SG; Reder, S; Saraste, A; Higuchi, T; Dzewas, G; Preissel, A; Huisman, M; Poethko, T; Schuster, T; Yu, M; Robinson, S; Casebier, D; Henke, J; Wester, HJ; Schwaiger, M
Abstract:
BACKGROUND: Positron-emission tomography (PET) tracers for myocardial perfusion are commonly labeled with short-lived isotopes that limit their widespread clinical use. 18F-BMS-747158-02 (18F-BMS) is a novel pyridaben derivative that was evaluated for assessment of myocardial perfusion by comparison with 13N-ammonia (13NH3) and with radioactive microspheres in a pig model. METHODS AND RESULTS: Fourteen pigs injected with 500 MBq of 13NH3 or 100 to 200 MBq of 18F-BMS underwent dynamic PET at rest...     »
Zeitschriftentitel:
Circulation
Jahr:
2009
Band / Volume:
119
Heft / Issue:
17
Seitenangaben Beitrag:
2333-42
Sprache:
eng
Volltext / DOI:
doi:10.1161/CIRCULATIONAHA.108.797761
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19380625
Print-ISSN:
0009-7322
TUM Einrichtung:
Institut für Medizinische Statistik und Epidemiologie; Klinik und Poliklinik für Nuklearmedizin
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