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Titel:

Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.

Dokumenttyp:
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
Autor(en):
Body, SC; Collard, CD; Shernan, SK; Fox, AA; Liu, KY; Ritchie, MD; Perry, TE; Muehlschlegel, JD; Aranki, S; Donahue, BS; Pretorius, M; Estrada, JC; Ellinor, PT; Newton-Cheh, C; Seidman, CE; Seidman, JG; Herman, DS; Lichtner, P; Meitinger, T; Pfeufer, A; Kääb, S; Brown, NJ; Roden, DM; Darbar, D
Abstract:
BACKGROUND: Atrial fibrillation (AF) is the most common adverse event following coronary artery bypass graft surgery. A recent study identified chromosome 4q25 variants associated with AF in ambulatory populations. However, their role in postoperative AF is unknown. We hypothesized that genetic variants in the 4q25 chromosomal region are independently associated with postoperative AF after coronary artery bypass graft surgery. METHODS AND RESULTS: Two prospectively collected cohorts of patients...     »
Zeitschriftentitel:
Circ Cardiovasc Genet
Jahr:
2009
Band / Volume:
2
Heft / Issue:
5
Seitenangaben Beitrag:
499-506
Sprache:
eng
Volltext / DOI:
doi:10.1161/CIRCGENETICS.109.849075
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/20031626
Print-ISSN:
1942-325X
TUM Einrichtung:
Institut für Humangenetik
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