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Title:

Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.

Document type:
Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
Author(s):
Body, SC; Collard, CD; Shernan, SK; Fox, AA; Liu, KY; Ritchie, MD; Perry, TE; Muehlschlegel, JD; Aranki, S; Donahue, BS; Pretorius, M; Estrada, JC; Ellinor, PT; Newton-Cheh, C; Seidman, CE; Seidman, JG; Herman, DS; Lichtner, P; Meitinger, T; Pfeufer, A; Kääb, S; Brown, NJ; Roden, DM; Darbar, D
Abstract:
BACKGROUND: Atrial fibrillation (AF) is the most common adverse event following coronary artery bypass graft surgery. A recent study identified chromosome 4q25 variants associated with AF in ambulatory populations. However, their role in postoperative AF is unknown. We hypothesized that genetic variants in the 4q25 chromosomal region are independently associated with postoperative AF after coronary artery bypass graft surgery. METHODS AND RESULTS: Two prospectively collected cohorts of patients...     »
Journal title abbreviation:
Circ Cardiovasc Genet
Year:
2009
Journal volume:
2
Journal issue:
5
Pages contribution:
499-506
Language:
eng
Fulltext / DOI:
doi:10.1161/CIRCGENETICS.109.849075
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20031626
Print-ISSN:
1942-325X
TUM Institution:
Institut für Humangenetik
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