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Title:

A modular framework for gene set analysis integrating multilevel omics data

Author(s):
Sass, S.; Büttner, F.; Müller, N. S.; Theis, F. J.
Abstract:
Modern high-throughput methods allow the investigation of biological functions across multiple ' omics' levels. Levels include mRNA and protein expression profiling as well as additional knowledge on, for example, DNA methylation and microRNA regulation. The reason for this interest in multi-omics is that actual cellular responses to different conditions are best explained mechanistically when taking all omics levels into account. To map gene products to their biological functions, public ontol...     »
Journal title:
Nucleic Acids Res.
Year:
2013
Journal volume:
41
Journal issue:
21
Pages contribution:
9622-9633
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