Benutzer: Gast  Login
Titel:

Mimicking Native Extracellular Matrix with Phytic Acid-Crosslinked Protein Nanofibers for Cardiac Tissue Engineering

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Ravichandran, R., Seitz, V., Reddy Venugopal, J., Sridhar, R., Sundarrajan, S., Mukherjee, S., Wintermantel, E., Ramakrishna, S.
Abstract:
A functional scaffold fabricated is developed from natural polymers, favoring regeneration of the ischemic myocardium. Hemoglobin/gelatin/fibrinogen (Hb/gel/fib) nanofibers are fabricated by electrospinning and are characterized for morphology, scaffold composition, functional groups and hydrophilicity. It is hypothesized that ex vivo pretreatment of mesenchymal stem cells (MSCs) using 5-azacytidine and such a functional nanofibrous construct having a high oxygen-carrying potential could lead to...     »
Stichworte:
cardiogenic differentiation crosslinkers ischemic myocardium mesenchymal stem cells phytic acid
Zeitschriftentitel:
Macromolecular Bioscience
Jahr:
2013
Band / Volume:
13
Heft / Issue:
3
Seitenangaben Beitrag:
366-375
Nachgewiesen in:
Web of Science
Reviewed:
ja
Volltext / DOI:
doi:10.1002/mabi.201200391
Format:
Text
 BibTeX