Benutzer: Gast  Login
Titel:

Decreased FOXP3 protein expression in patients with asthma.

Dokumenttyp:
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Provoost, S; Maes, T; van Durme, YM; Gevaert, P; Bachert, C; Schmidt-Weber, CB; Brusselle, GG; Joos, GF; Tournoy, KG
Abstract:
T-regulatory cells (T(reg)) are important in balancing immune responses and maintaining peripheral tolerance. Current evidence suggests that asthma is characterized by a relative deficiency in T(reg), allowing T helper 2 cells to expand. In this study, we aimed to evaluate circulating T(reg), defined by the protein FOXP3, in both control subjects and patients with stable asthma.Peripheral blood mononuclear cells (PBMC) of control (n = 14) and asthmatic patients (n = 29) were labeled for CD4, CD2...     »
Zeitschriftentitel:
Allergy
Jahr:
2009
Band / Volume:
64
Heft / Issue:
10
Seitenangaben Beitrag:
1539-46
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1398-9995.2009.02056.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19392991
Print-ISSN:
0105-4538
TUM Einrichtung:
Molekulare Allergologie (Prof. Schmidt-Weber)
 BibTeX