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- Title:
Hitting the right button: MAVS-mediated defense against HAV infection.
- Document type:
- Journal Article
- Author(s):
- Knolle, Percy A
- Abstract:
- Studying the immune response against infection with hepatitis viruses is hampered by the lack of suitable preclinical model systems. A recent publication in Science identifies the cytosolic adapter molecule MAVS as being responsible for species restriction of infection with hepatitis A virus as well as linking cytosolic immune sensing in infected hepatocytes with innate effector functions and protective adaptive immunity.
- Journal title abbreviation:
- Cell Res
- Year:
- 2017
- Journal volume:
- 27
- Journal issue:
- 1
- Pages contribution:
- 7-8
- Language:
- eng
- Fulltext / DOI:
- doi:10.1038/cr.2016.139
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/27886168
- Print-ISSN:
- 1001-0602
- TUM Institution:
- Roman Herzog Comprehensive Cancer Center
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