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Title:

Hepatic immune regulation and its involvement in viral hepatitis infection.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review
Author(s):
Knolle, Percy A; Thimme, Robert
Abstract:
The liver has unique immune regulatory functions that promote the induction of tolerance rather than responses to antigens encountered locally. These functions are mediated by local expression of coinhibitory receptors and immunosuppressive mediators that help prevent overwhelming tissue damage. Over the years, we have gained more insight into the local regulatory cues that determine the functional complexity of immune responses regulated locally in the liver. Both the unique hepatic microenviro...     »
Journal title abbreviation:
Gastroenterology
Year:
2014
Journal volume:
146
Journal issue:
5
Pages contribution:
1193-207
Language:
eng
Fulltext / DOI:
doi:10.1053/j.gastro.2013.12.036
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/24412289
Print-ISSN:
0016-5085
TUM Institution:
Roman Herzog Comprehensive Cancer Center
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