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Title:

Global transcriptional characterization of CD8+ T cell memory.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review; Review
Author(s):
Böttcher, Jan; Knolle, Percy A
Abstract:
The differentiation of memory CD8T cells after acute infections comprises generation of functionally distinct populations that either have proliferative potential or display cytotoxic effector functions and that either recirculate into lymphoid tissues or remain tissue-resident. The development of these functionally distinct cell populations is dictated by defined signals from the microenvironment that result in a coordinated expression of a network of transcription factors, which determine the...     »
Journal title abbreviation:
Semin Immunol
Year:
2015
Journal volume:
27
Journal issue:
1
Pages contribution:
4-9
Language:
eng
Fulltext / DOI:
doi:10.1016/j.smim.2015.03.001
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25841628
Print-ISSN:
1044-5323
TUM Institution:
Roman Herzog Comprehensive Cancer Center
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