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Title:

Design Principles as a Guide for Constraint Based and Dynamic Modeling: Towards an Integrative Workflow

Document type:
Zeitschriftenaufsatz
Author(s):
Sehr, Christiana; Kremling, Andreas; Marin-Sanguino, Alberto
Abstract:
During the last 10 years, systems biology has matured from a fuzzy concept combining omics, mathematical modeling and computers into a scientific field on its own right. In spite of its incredible potential, the multilevel complexity of its objects of study makes it very difficult to establish a reliable connection between data and models. The great number of degrees of freedom often results in situations, where many different models can explain/fit all available datasets. This has resulted in a...     »
Keywords:
BST; FBA; systems biology; thermodynamic feasibility analysis
Journal title:
Metabolites
Year:
2015
Year / month:
2015-10
Language:
en
Fulltext / DOI:
doi:10.3390/metabo5040601
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26501332
WWW:
http://www.ncbi.nlm.nih.gov/pubmed/26501332
Date of publication:
16.10.2015
TUM Institution:
FG für Systembiotechnologie
Ingested:
07.12.2015
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