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Titel:

Etiopathogenesis of Otosclerosis

Autor(en):
Niedermeyer, Hans P.; Arnold, Wolfgang
Abstract:
Otosclerosis is a frequent cause of nonsyndromic hearing loss which affects exclusively the human temporal bone. Various etiopathogenetic hypotheses have been proposed. The major hypotheses considered are genetic factors, immunologic factors and viral infection. Since the familial incidence of otosclerosis is known a recent genetic analysis has given evidence of three otosclerosis genes (OTSC1–3). Mutations in the collagen gene COL1A1 have been found in one large family with several cases of oto...     »
Stichworte:
Otosclerosis; Collagen; Heredity; Measles virus
Zeitschriftentitel:
ORL
Jahr:
2002
Band / Volume:
64
Heft / Issue:
2
Seitenangaben Beitrag:
114--119
Volltext / DOI:
doi:10.1159/000057789
Verlag / Institution:
S. Karger AG
Verlagsort:
Basel, Switzerland
Print-ISSN:
1423-0275
E-ISSN:
1423-0275
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
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