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Title:

Mouse Models of Atopic Eczema Critically Evaluated

Author(s):
Gutermuth, Jan; Ollert, Markus; Ring, Johannes; Behrendt, Heidrun; Jakob, Thilo
Abstract:
Atopic eczema (AE) is a chronic relapsing inflammatory skin disorder with increasing prevalence in Western societies. Even though we have made considerable progress in understanding the cellular and molecular nature of cutaneous inflammation, the precise pathomechanisms of AE still remain elusive. Experimental animal models are indispensable tools to study the pathogenic mechanisms and to test novel therapeutic approaches in vivo. For AE a considerable number of mouse models have been proposed a...     »
Keywords:
Models; animal/mouse; Eczema; atopic; Dermatitis; atopic; Atopic eczema/dermatitis syndromes
Journal title:
International Archives of Allergy and Immunology
Year:
2004
Journal volume:
135
Journal issue:
3
Pages contribution:
262--276
Fulltext / DOI:
doi:10.1159/000082099
Publisher:
S. Karger AG
Publisher address:
Basel, Switzerland
Print-ISSN:
1423-0097
E-ISSN:
1423-0097
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
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