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Titel:

Islets of Langerhans Are Protected from Inflammatory Cell Recruitment during Reperfusion of Rat Pancreas Grafts

Autor(en):
Preissler, G.; Massberg, S.; Eichhorn, M. E.; Waldner, H.; Loehe, F.; Winter, H.; Messmer, K.
Abstract:
Background: Ischemia/reperfusion (I/R) injury plays a pivotal role in the development of graft pancreatitis, with ischemia time representing one of its crucial factors. However, it is unclear, whether exocrine and endocrine tissue experience similar inflammatory responses during pancreas transplantation (PTx). This study evaluated inflammatory susceptibilities of islets of Langerhans (ILH) and exocrine tissue after different preservation periods during early reperfusion. Methods: PTx was perform...     »
Stichworte:
Pancreas transplantation; Microcirculation; Leukocytes; Islets of Langerhans; Ischemia/reperfusion
Zeitschriftentitel:
European Surgical Research
Jahr:
2010
Band / Volume:
44
Heft / Issue:
3-4
Seitenangaben Beitrag:
192--200
Volltext / DOI:
doi:10.1159/000302732
Verlag / Institution:
S. Karger AG
Verlagsort:
Basel, Switzerland
Print-ISSN:
1421-9921
E-ISSN:
1421-9921
Hinweise:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
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