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Title:

The role of liver sinusoidal cells in local hepatic immune surveillance.

Document type:
Journal Article; Review; Review
Author(s):
Wohlleber, Dirk; Knolle, Percy A
Abstract:
Although the liver's function as unique immune organ regulating immunity has received a lot of attention over the last years, the mechanisms determining hepatic immune surveillance against infected hepatocytes remain less well defined. Liver sinusoidal cells, in particular, liver sinusoidal endothelial cells (LSECs) and Kupffer cells (KCs), serve as physical platform for recruitment and anchoring of blood-borne immune cells in the liver. Liver sinusoidal cells also function as portal of entry fo...     »
Journal title abbreviation:
Clin Transl Immunology
Year:
2016
Journal volume:
5
Journal issue:
12
Pages contribution:
e117
Language:
eng
Fulltext / DOI:
doi:10.1038/cti.2016.74
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28090319
TUM Institution:
Roman Herzog Comprehensive Cancer Center
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