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Title:

Immunological functions of liver sinusoidal endothelial cells.

Document type:
Journal Article; Review; Review
Author(s):
Knolle, Percy A; Wohlleber, Dirk
Abstract:
Liver sinusoidal endothelial cells (LSECs) line the liver sinusoids and separate passenger leukocytes in the sinusoidal lumen from hepatocytes. LSECs further act as a platform for adhesion of various liver-resident immune cell populations such as Kupffer cells, innate lymphoid cells or liver dendritic cells. In addition to having an extraordinary scavenger function, LSECs possess potent immune functions, serving as sentinel cells to detect microbial infection through pattern recognition receptor...     »
Journal title abbreviation:
Cell Mol Immunol
Year:
2016
Journal volume:
13
Journal issue:
3
Pages contribution:
347-53
Language:
eng
Fulltext / DOI:
doi:10.1038/cmi.2016.5
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27041636
Print-ISSN:
1672-7681
TUM Institution:
Roman Herzog Comprehensive Cancer Center
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