Benutzer: Gast  Login
Titel:

Checkpoint Inhibition in Head and Neck Cancer: Immune Therapeutic Options, Limitations, and Beyond.

Dokumenttyp:
Journal Article; Review
Autor(en):
Höchst, Bastian; Knolle, Percy A
Abstract:
The immune system functions to defend the organism against infectious microorganisms but also against transformed cells. This key role of the immune system, in particular cancer-specific T cells, in eliminating cancer cells is compromised by various immune escape strategies employed by cancer cells and the cancer microenvironment. Here, we review the current knowledge about the immune escape mechanisms of cancer and the attempts to reconstitute cancer-specific immunity by using checkpoint inhibi...     »
Zeitschriftentitel:
ORL J Otorhinolaryngol Relat Spec
Jahr:
2017
Band / Volume:
79
Heft / Issue:
1-2
Seitenangaben Beitrag:
24-33
Sprache:
eng
Volltext / DOI:
doi:10.1159/000455810
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28231588
Print-ISSN:
0301-1569
TUM Einrichtung:
Roman Herzog Comprehensive Cancer Center
 BibTeX